• To our knowledge, these are the first cases of almost complete Netherton's syndrome in two adult brothers born of consanguineous parents. The aromatic retinoid, etretinate, although initially worsened the eczematous manifestations, proved to be capable of reducing the primary skin lesions in one patient.
(Arch Dermatol 1984;120:220-222)
Caputo R, Vanotti P, Bertani E. Netherton's Syndrome in Two Adult Brothers. Arch Dermatol. 1984;120(2):220-222. doi:10.1001/archderm.1984.01650380080016