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May 1984

Monoclonal Gammopathy in Sézary SyndromeReport of Three Cases and Review of the Literature

Author Affiliations

From the Department of Dermatology (Dr Winkelmann) and the Division of Hematology and Internal Medicine (Dr Kyle), Mayo Clinic and Mayo Foundation, Rochester, Minn, and the Clinique Dermatologique, Hôpital St Louis, Paris (Drs Venencie and Puissant). Dr Venencie is presently a visiting clinician in the Department of Dermatology, Mayo Clinic and Mayo Foundation.

Arch Dermatol. 1984;120(5):605-608. doi:10.1001/archderm.1984.01650410047014

• Three patients with Sézary syndrome had monoclonal gammopathy: two had gammopathy of unknown significance and one had myeloma. The frequency of the association of Sézary syndrome and monoclonal gammopathy seems to be lower than previously suggested. However, it does emphasize that the presence of T-cell cutaneous disease does not preclude B-cell clonal proliferation.

(Arch Dermatol 1984;120:605-608)