† Generalized staphylococcal scalded skin syndrome (SSSS) is a toxin-related epidermolytic disease that predominantly affects previously healthy infants and children younger than 5 years. In contrast, the majority of the reported adult cases have been associated with underlying diseases, suggesting that immunosuppression and renal insufficiency are important predisposing conditions for this age group. We report herein a case of adult-type SSSS in an anephric 10-year-old boy. Patients undergoing hemodialysis who have chronic renal failure may be uniquely predisposed to the SSSS by virtue of their decreased glomerular filtration rate, associated uremic immunodeficiency, and a high incidence of Staphylococcus aureus bacteremia.
(Arch Dermatol 1984;120:912-918)
Borchers SL, Gomez EC, Isseroff RR. Generalized Staphylococcal Scalded Skin Syndrome in an Anephric Boy Undergoing Hemodialysis. Arch Dermatol. 1984;120(7):912-918. doi:10.1001/archderm.1984.01650430098018