• A study of tinea versicolor organisms was conducted in one patient by scanning electron microscopy. Morphologic changes in the organisms during treatment with topical clotrimazole and miconazole nitrate consisted of initial wrinkling of the surface, followed by fragmentation. These changes may have reflected cell wall alterations resulting from inhibited ergosterol synthesis induced by both treatment agents. The two drugs were effective in eliminating the organisms.
(Arch Dermatol 1984;120:1057-1058)
McDaniel DH, Welton WA. Scanning Electron Microscopic Evaluation of Tinea VersicolorEffects of Treatment With Miconazole Nitrate and Clotrimazole. Arch Dermatol. 1984;120(8):1057-1058. doi:10.1001/archderm.1984.01650440087025