[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
September 1984

Oral Isotretinoin TherapyUse in a Patient With Multiple Cutaneous Squamous Cell Carcinomas and Keratoacanthomas

Author Affiliations

From the Sections of Dermatology (Drs Levine and Miller), Hematology/Oncology, and the Cancer Center (Dr Meyskens), University of Arizona Health Sciences Center, Tucson.

Arch Dermatol. 1984;120(9):1215-1217. doi:10.1001/archderm.1984.01650450097029

• An 83-year-old woman with multiple squamous cell carcinomas and keratoacanthomas of the legs was treated with orally administered isotretinoin (13 cis-retinoic acid). Complete regression of the tumors was noted during the initial six-month treatment period. In the subsequent 36 months, four new cutaneous tumors were excised. There have been no recurrences of lesions that regressed while the patient was receiving retinoid therapy.

(Arch Dermatol 1984;120:1215-1217)