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September 1984

Skin Permeability

Author Affiliations

San Diego


by H. Schaefer, A. Zesch, and G. Stuttgen, 355 pp, with 139 illus, $62, New York, Springer-Verlag Inc, 1982.

Arch Dermatol. 1984;120(9):1247. doi:10.1001/archderm.1984.01650450129044

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


This text is a most thorough and up-to-date review of percutaneous absorption. Schaefer and his collaborators have meticulously reviewed the literature and organized a marvelous presentation that will be deeply appreciated by anyone interested in the field.

It is comprehensible to readers in different disciplines, including pharmacologists, toxicologists, dermatologists, pharmaceutical scientists, and theoreticians in the field. An exhaustive list of references will be extremely helpful to anyone wanting to know what has happened in percutaneous absorption during the past 50 years.

A detailed tabulation of individual chemicals has been investigated, and the appropriate references for each chemical are included. A tabulation of these individual chemicals is provided for reference purposes.

The concept of percutaneous absorption has recently found many advocates, not only because the biologic effects of topical dermatologic preparations may be enhanced, but also because there is an enormous field in pharmacology that includes systemic treatment by topical application

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