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April 1985

Skin Peeling Syndrome in a Kurdish Family

Author Affiliations

From the Department of Dermatology, Hadassah University Hospital, Jerusalem.

Arch Dermatol. 1985;121(4):545-546. doi:10.1001/archderm.1985.01660040129027

Skin peeling syndrome (SPS) is a rare genodermatosis, with variable age of onset from birth1 to adulthood.2 Clinically, it is characterized by a pruritic or nonpruritic spontaneous superficial peeling of the skin, which sometimes is accompanied by erythema or vesiculation.2 The skin involvement is usually general, but in some patients the scalp, face, palms, and soles may be unaffected.2 Seasonal changes have been reported.2,3 The histologic picture is characterized by separation of the epidermis between the stratum corneum and the stratum granulosum.3 We describe herein two siblings of a Jewish family originating from Kurdistan who were affected by SPS.

Report of Cases 

Case 1.—  The proband, an 8-year-old boy, was referred to the skin clinic for itching, redness, and peeling of the skin. Redness, peeling of the neck, antecubital and popliteal areas, and wrists, developed four days after his birth; later on, redness and peeling

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