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Article
June 1985

Monoclonal Antibody Studies in the Skin Lesions of Patients With Anetoderma

Author Affiliations

From the Department of Dermatology, Mayo Clinic and Mayo Foundation, Rochester, Minn. Dr Venencie is a visiting clinician from the Clinique Dermatologique (Pr A. Puissant), Hôpital Saint Louis, Paris.

Arch Dermatol. 1985;121(6):747-749. doi:10.1001/archderm.1985.01660060061021
Abstract

• In all five patients studied, monoclonal antibody studies of cryostat sections of skin biopsy specimens of anetoderma lesions revealed inflammatory cells reacting with anti-Leu-1, pan-T-cell antibody, and anti-Leu-3a, the helper/inducer T-cell antibody. Small numbers of suppressor cells were present in only three biopsy specimens. Four specimens showed OKM, antibody-reacting cells (monocytes). The age of the lesion was not correlated with inflammation or the T-cell subsets identified.

(Arch Dermatol 1985;121:747-749)

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