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June 1985

Sweet's Syndrome in Subacute Cutaneous Lupus Erythematosus

Author Affiliations


From the Dermatology Service, Department of Medicine, Letterman Army Medical Center, Presidio of San Francisco.

Arch Dermatol. 1985;121(6):789-791. doi:10.1001/archderm.1985.01660060103031

• A 67-year-old man being treated with prednisone, 15 mg/day, for subacute cutaneous lupus erythematosus developed widespread, tender, erythematous plaques, arthralgias, and fever. Clinically, the cutaneous lesions mimicked lupus erythematosus. The diagnosis of acute febrile neutrophilic dermatosis, or Sweet's syndrome, was confirmed by histologic examination of three biopsy specimens, which revealed prominent dermal edema, extensive infiltration with intact and karyorrhectic polymorphonuclear leukocytes, and perivascular and appendiceal lymphocytes in the absence of leukocytoclastic angiitis.

(Arch Dermatol 1985;121:789-791)