• Follicular hyperkeratosis was observed in a patient with multiple myeloma. This keratosis is considered to be a cutaneous manifestation of multiple myeloma, since similar cases have been observed before. In addition, the patient had cutaneous, ocular, and articular signs and symptoms of cryocrystalglobulinemia, ie, cutaneous vasculitis, blurring, and joint swellings.
(Arch Dermatol 1985;121:795-798)
Lukitsch O, Gebhardt K, Kövary PM. Follicular Hyperkeratosis and Cryocrystalglobulinemia SyndromeOccurrence in a Patient With Multiple Myeloma. Arch Dermatol. 1985;121(6):795-798. doi:10.1001/archderm.1985.01660060109033