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July 1985

Nocardia asteroides Infection With Dissemination to Skin and Joints

Author Affiliations

From the Department of Medicine, Division of Dermatology, Ohio State University, Columbus.

Arch Dermatol. 1985;121(7):898-900. doi:10.1001/archderm.1985.01660070088022

• A 56-year-old diabetic woman developed multiple cutaneous lesions and septic arthritis secondary to disseminated Nocardia asteroides pulmonary infection. The diagnosis was made rapidly by Gram's and acid-fast stains of pus, sputum, and synovial fluid and later confirmed by cultures. Sulfonamides are the drugs of choice for nocardiosis, and this patient had a complete response to two weeks of intravenous trimethoprim and sulfamethoxasole followed by three months of oral therapy.

(Arch Dermatol 1985;121:898-900)