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September 1985

A Histologic Study of Epithelial Dysplasia in Oral Lichen Planus

Author Affiliations

From the Department of Oral Medicine and Oral Pathology, Harvard School of Dental Medicine, Boston.

Arch Dermatol. 1985;121(9):1132-1136. doi:10.1001/archderm.1985.01660090046011

• One hundred cases of oral lichen planus were reviewed together with 100 nonspecific oral mucosal inflammatory lesions as a control group. The presence of dysplasia was noted, using well-established histologic criteria. Mild dysplasia was found in 57% of cases, moderate dysplasia in 9%, and severe dysplasia in 2% of cases. In the control group, mild dysplasia was observed in 32% of cases, moderate in 10%, and severe dysplasia was not present. It is suggested that, while mild or moderate dysplasia may not indicate precancerous potential, severe dysplasia in lichen planus may signify the development of a precancerous lesion.

(Arch Dermatol 1985;121:1132-1136)