• We treated two unrelated boys with ichthyosis follicularis, a rare skin disorder characterized by extensive noninflammatory spiny follicular hyperkeratoses, severe photophobia, and generalized noncicatricial alopecia. This disorder must be differentiated from keratosis follicularis spinulosa decalvans; ulerythema ophryogenes; keratosis pilaris rubra atrophicans faciei; atrichia with papular lesions; atrophodermia vermiculata; and keratitis, ichthyosis, and deafness syndrome, all of which share some clinical features. Ichthyosis follicularis with alopecia and photophobia appears to be a familial disorder, but too few cases have been reported to establish the exact mode of inheritance.
(Arch Dermatol 1985;121:1167-1174)
Eramo LR, Esterly NB, Zieserl EJ, Stock EL, Herrmann J. Ichthyosis Follicularis With Alopecia and Photophobia. Arch Dermatol. 1985;121(9):1167-1174. doi:10.1001/archderm.1985.01660090081019