• A 47-year-old black man had typical papulonodular lesions of lymphomatoid papulosis (LyP) with concurrent plaque-stage mycosis fungoides (MF). Both diagnoses were confirmed histologically. This supports the concept that LyP is part of the spectrum of cutaneous T-cell lymphoproliferative disorders. The patient also had a large nodule and a deeply infiltrated plaque, each of which exhibited a deep granulomatous reaction. These were interpreted as representing granulomatous MF. Clinically, there was an evolution from a predominance of LyP lesions to a predominance of MF plaques. Topical carmustine therapy resulted in a substantial decrease in the number and size of both LyP and MF lesions. Both lesion types involuted with hypopigmentation.
(Arch Dermatol 1985;121:1175-1180)
Kardashian JL, Zackheim HS, Egbert BM. Lymphomatoid Papulosis Associated With Plaque-Stage and Granulomatous Mycosis Fungoides. Arch Dermatol. 1985;121(9):1175-1180. doi:10.1001/archderm.1985.01660090089020