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October 1985

Perforating Pseudoxanthoma Elasticum Associated With Chronic Renal Failure and Hemodialysis

Author Affiliations

From the Department of Dermatology, Stanford (Calif) University Medical Center.

Arch Dermatol. 1985;121(10):1321-1322. doi:10.1001/archderm.1985.01660100101025

• A patient with hypertension and chronic renal failure of an undetermined cause who was undergoing hemodialysis developed bilateral crusted, focally eroded plaques on her breasts. A biopsy specimen of the lesional skin revealed typical histologic changes of pseudoxanthoma elasticum, with epidermal perforation. A biopsy specimen of lesion-free skin revealed characteristics typical of pseudoxanthoma elasticum. Perforating pseudoxanthoma elasticum should be added to the growing list of cutaneous disorders that occur in patients with chronic renal failure who are undergoing hemodialysis.

(Arch Dermatol 1985;121:1321-1322)