To the Editor.—
Wrinkles are the most common sign of aging. Wrinkles also form in some congenital or acquired skin disorders.1-3 In general, wrinkles are bilateral and symmetrical, but one case of unilateral wrinkles has been described.4 The dermal connective tissue, particularly elastic tissue, has been suggested to play an important role in the formation of wrinkles. There have been few studies on wrinkles, and the word wrinkle is strangely absent from the indexes of medical literature.The purpose of this letter is to indicate that there are two types of wrinkles in aged persons, depending on the clinical and histologic findings.
Subjects and Methods.—
Wrinkles of six aged persons (four men and two women aged 67 to 82 years) were investigated. The subjects had many deep wrinkles symmetrically on the face and neck, most of which did not disappear by stretching transversely to the direction of the
Tsuji T, Yorifuji T, Hayashi Y, Hamada T. Two Types of Wrinkles in Aged Persons. Arch Dermatol. 1986;122(1):22-23. doi:10.1001/archderm.1986.01660130024017