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May 1986

Punch Biopsy Wounds Treated With Monsel's Solution or a Collagen MatrixA Comparison of Healing

Author Affiliations

From the Department of Dermatology, Columbia-Presbyterian Medical Center, New York (Dr Armstrong), and the Helitrex Corp, Princeton, NJ (Drs Nichols and Pachance).

Arch Dermatol. 1986;122(5):546-549. doi:10.1001/archderm.1986.01660170076023

• Adjacent punch biopsy wounds in 20 subjects were treated with a collagen matrix or Monsel's solution. Both techniques were easy to use and were hemostatically effective. The collagen matrix produced less inflammation, had a lower incidence of wound infection, was associated with a faster reepithelialization rate, and healed with a modestly better appearance at four weeks than did Monsel's solution.

(Arch Dermatol 1986;122:546-549)