• Human T-cell lymphotropic virus type I (HTLV-I) is a human retrovirus that can transform T-helper lymphocytes and is etiologically associated with adult T-cell lymphoma/leukemia. Mycosis fungoides represents a primary cutaneous lymphoma of helper T-cell origin, while chronic lymphocytic leukemia is generally considered to be a neoplastic B-lymphocyte disorder. Our patient had HTLV-I with coexistent mycosis fungoides and B-cell chronic lymphocytic leukemia. The concurrent lymphoid proliferations may represent HTLV-I-associated abnormalities of immunoregulation.
(Arch Dermatol 1986;122:568-571)
Peterman A, Myles , Staal S, Bradley , Striecher H, Schüpbach J, Resnick L. Evidence for HTLV-I Associated With Mycosis Fungoides and B-Cell Chronic Lymphocytic Leukemia. Arch Dermatol. 1986;122(5):568-571. doi:10.1001/archderm.1986.01660170098028