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November 1986

Fever and Hypotrichosis in a Newborn

Author Affiliations

Baylor College of Medicine, Houston

Arch Dermatol. 1986;122(11):1325-1326. doi:10.1001/archderm.1986.01660230117024

REPORT OF A CASE  A male infant was born to a 36-year-old woman at 43 weeks' gestational age, following an otherwise uncomplicated pregnancy. Birth weight was 2810 g, and Apgar scores were 2, 4, and 7 at one, five, and ten minutes, respectively. Neonatal physical examination was remarkable for an infant without any scalp hair, eyelashes, or eyebrows who was in respiratory distress as a result of meconium aspiration. The patient was intubated for five days and developed persistent pulmonary hypertension. In addition, the infant had difficulty feeding. A barium swallow showed this to be the result of swallowing incoordination and aspiration. However, these eventually resolved spontaneously, and the infant was feeding well.Beginning in the second week of life, the patient developed recurrent fevers, which on two occasions reached a maximum of 42°C (107°F); these responded to sponge baths and acetaminophen therapy. Antibiotic therapy was begun empirically but was

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