[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.197.90.95. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
December 1986

Erythrokeratodermia Variabilis

Author Affiliations

Second Department of Dermatology University of Vienna Medical School A-1090 Vienna, Austria

Arch Dermatol. 1986;122(12):1356. doi:10.1001/archderm.1986.01660240018003
Abstract

To the Editor.—  I read with interest the article in the April issue of the Archives on successful treatment of erythrokeratodermia variabilis (EKV) with isotretinoin.1 In 1981, we reported a case of EKV that was treated successfully with etretinate.2 In our case, however, we could observe no abnormalities in the quantity of keratinosomes (Odland bodies) before treatment. Our results for tritiated thymidine autoradiography and electron microscopy were indicative of a proliferation hyperkeratosis together with retention hyperkeratosis. Whether the controversial results in our patient and Rappaport's patient are caused by different or insufficient techniques in investigation, or whether several morphological subtypes of EKV exist, remains unclear.

First Page Preview View Large
First page PDF preview
First page PDF preview
×