• A man with a six-year history of intermittent burning sensations in his legs, hypothyroidism, and peripheral neuropathy also had hypertrichosis, hyperpigmentation, Terry nails, and taut thickened skin of the extremities. Discovery of a plasma cell tumor led to recognition of the Crow-Fukase syndrome, and appropriate treatment with melphalan and prednisone.
(Arch Dermatol 1987;123:85-87)
Shelley WB, Shelley ED. The Skin Changes in the Crow-Fukase (POEMS) SyndromeA Case Report. Arch Dermatol. 1987;123(1):85-87. doi:10.1001/archderm.1987.01660250091026