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March 1987

Actinic Reticuloid: An Immunohistochemical Study

Author Affiliations

Department of Dermatology Hamamatsu University School of Medicine Hamamatsu 431-31, Japan

Arch Dermatol. 1987;123(3):296-297. doi:10.1001/archderm.1987.01660270028006

To the Editor.—  One of the distressing conditions of actinic reticuloid (AR) is its persistence for long durations without any demonstrable contact with the photoallergen. It is hypothesized that autoreactive cells are activated in the skin lesion of AR.1 We report a case of AR with the immunohistochemical study of the affected site.

Report of a Case.—  A 75-year-old Japanese man had a four-year history of pruritic rash that first appeared on the sun-exposed areas of his body and then extended to the covered areas within two years. There was no family history of dermatoses.Physical examination showed scattered, violaceous papules on the face (Figure) and moderate lichenification of the skin over the light-exposed area of the neck, the hands, and the nape. Of the peripheral blood mononuclear cells, Scattered papules on cheek and chin.Composition of Dermal Infiltrating Cells* % Reactive Cells in Interstitium Site of Biopsy Leu-1 Leu-2a

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