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May 1987

Pinkus' Guide to Dermatohistopathology

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ed 4, edited by Amir H. Mehregan, 624 pp, 12 color, 648 halftone, and 22 line illus, $15, East Norwalk, Conn, Appleton-Century-Crofts, 1986

Arch Dermatol. 1987;123(5):671. doi:10.1001/archderm.1987.01660290143035

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The fourth edition of Pinkus' Guide to Dermatohistopathology represents a revision of this widely read textbook five years after publication of the previous edition in 1981. The changes are quite subtle; the most notable alterations include an enlarged chapter on immunopathology of the skin, slightly expanded discussions of ichthyosiform dermatoses, dysplastic nevi, and melanoma, and updated references scattered throughout the book.

The chapter on immunopathology of the skin, written by Dr Keyoumars Soltani, is well organized and contains useful information regarding immunofluorescence and immunoperoxidase techniques as well as discussions of immunopathologic findings in all immunologically mediated vesiculobullous dermatoses and connective tissue diseases. This chapter represents the major revision to the previous edition and, as such, has its shortcomings. Immunoelectron micrographs are absent and would have been useful in demonstrating localization of antigens within the basement membrane zone. Evaluation of antigen expression through immunoperoxidase techniques is a major diagnostic and investigative

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