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June 1987

Dapsone as Initial Treatment in Superficial PemphigusReport of Nine Cases

Author Affiliations

From the Clinique de Dermatologie, Hôpital St Charles, Montpellier, France (Drs Basset, Guillot, Meynadier, and Guilhou), and the Hôpital de Nîmes (France) (Dr Michel). Dr Basset is now with the Uniformed Services University of the Health Sciences-F. Edward Hébert School of Medicine, Bethesda, Md.

Arch Dermatol. 1987;123(6):783-785. doi:10.1001/archderm.1987.01660300105021

• Nine cases of superficial pemphigus that were treated by dapsone as the initial mode of therapy are reported. Five patients, all having low or negative serum anti-intercellular cement substance antibody titers, responded dramatically, while the other four patients, showing high titers of anti-intercellular cement substance antibodies, did not respond to this treatment. Complications of therapy were observed in three cases.

(Arch Dermatol 1987;123:783-785)