• Dermochondrocorneal dystrophy (François' syndrome) is an extremely rare disorder characterized by firm, nodular lesions involving the hands and the face; osteochondrodystrophy of the peripheral extremital bones, resulting in limitation of movement; and corneal dystrophy marked by white or brownish opacities. A nonfamilial case of dermochondrocorneal dystrophy was studied in a 45-year-old woman who had severe involvement of the gingival and palatal mucous membranes.
(Arch Dermatol 1988;124:424-428)
Caputo R, Sambvani N, Monti M, Cavicchini S, Carrassi A, Ratiglia R. Dermochondrocorneal Dystrophy (François' Syndrome)Report of a Case. Arch Dermatol. 1988;124(3):424-428. doi:10.1001/archderm.1988.01670030090029