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Article
April 1988

Diffuse Cutaneous Reticulohistiocytosis in a Child With Tuberous Sclerosis

Author Affiliations

From the I Dermatologic Clinic and Pediatric Dermatology, University of Milan (Italy).

Arch Dermatol. 1988;124(4):567-570. doi:10.1001/archderm.1988.01670040069026
Abstract

• Reticulohistiocytosis, a rare disorder occurring almost exclusively in adults, was seen in "pure" diffuse cutaneous form in an 8-year-old boy who had had tuberous sclerosis since birth. The clinical features consisted of many papulonodular lesions, located mainly on the trunk and to a lesser extent on the head and limbs. Histologic findings were distinctive. Ultrastructural examination revealed the presence of pleomorphic cytoplasmic inclusions in almost all of the giant histiocytic cells of the infiltrate.

(Arch Dermatol 1988;124:567-570)

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