To the Editor.—
A number of reports have dealt with unexpected disorders secondary to radiotherapy. Most of these have emphasized the development of follicular-based acneform eruptions characterized by comedones, papules, pustules, and cysts,1-3 but more recently, Burns4 described a patient in whom multiple digitate keratoses appeared after radiotherapy.We describe a patient in whom a miliarialike eruption developed confined to the radiotherapy field, which showed extensive keratinization concentrated in the eccrine ducts and their openings. This appears to be a distinct radiotherapy-induced keratotic disorder that may have been conditioned by previous chemotherapy.
Report of a Case.—
A 48-year-old man underwent a laparotomy in May 1981 for abdominal pain thought to be due to a pseudocyst of the pancreas. Biopsies and subsequent staging revealed stage 2E non-Hodgkin's lymphoma of a poorly differentiated lymphocytic type. He was treated with nine courses of doxorubicin hydrochloride, teniposide, cyclophosphamide,
Kossard S, Commens CA. Keratotic Miliaria Precipitated by Radiotherapy. Arch Dermatol. 1988;124(6):855-856. doi:10.1001/archderm.1988.01670060013007