To the Editor.—
Since its description by Ramirez in 1957 under the name ashy dermatosis, erythema dyschromicum perstans (EDP) remains a discussed clinical entity of unknown cause.1-4 A relationship between EDP and lichen planus5 (LP) has been suggested, allowing some authors to propose the term lichen planus pigmentosus.6 We report a further case of EDP following human immunodeficiency virus (HIV) seroconversion.
Report of a Case.—
A 6-year-old boy was referred to our institution in January 1987, for the evaluation of a cutaneous pigmentary disturbance first noted in January 1984. The skin lesions were preceded by transient, nonpruritic, erythematous macules with generalized lymphadenopathies and splenomegaly. The patient suffered from hemophilia B, with an HIV seroconversion demonstrated in June 1983 by the enzyme-linked immunosorbent assay (ELISA) and confirmed by Western blotting, whereas ELISA performed on serum stored since September 1982 was negative. On examination, there was a brownish,
Venencie PY, Lemay D, Verroust F. Erythema Dyschromicum Perstans Following Human Immunodeficiency Virus Seroconversion in a Child With Hemophilia B. Arch Dermatol. 1988;124(7):1013-1014. doi:10.1001/archderm.1988.01670070015007