To the Editor.—
Although the majority of cases are idiopathic, the papular or papulovesicular acrolocated syndromes (PAS) that were first described by Crosti and Gianotti in 19641 are associated with hepatitis B surface antigenemia and a variety of other conditions, including Henoch-Schönlein purpura,2 smallpox and poliovirus vaccinations, and numerous viral illnesses.3,4 Rotavirus has not been associated with PAS, or recognized as a cause of viral exanthem in childhood. We describe two children with acute rotavirus gastroenteritis associated with PAS.
Report of Cases.—
An 18-month-old boy and a 19-month-old girl were seen with a PAS of three and seven days duration, respectively. The lesions had started on the lower legs in both patients and in a few days had spread to the face, arms, and buttocks. There was no history of fever, but both patients showed diarrhea four and seven days prior to the onset of the eruption.
Annalisa P, Antonella B, Claudio V, Giampaolo R, Massimo M. Papular or Papulovesicular Syndromes. Arch Dermatol. 1988;124(9):1444-1445. doi:10.1001/archderm.1988.01670090086026