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November 1988

Repopulation of Pigment Cells in Patients With Vitiligo

Author Affiliations

Yale University School of Medicine Department of Dermatology 333 Cedar St PO Box 3333 New Haven, CT 06511

Arch Dermatol. 1988;124(11):1701-1702. doi:10.1001/archderm.1988.01670110061012

There of skin from pigmented sites into white patches of patients with vitiligo or other conditions of hypopigmentation.1-10 Exchange grafts between light and dark areas in vitiligo were performed for experimental reasons so as to learn more about the origins of the disease, as well as to provide a new, successful treatment. Falabella6 pioneered the use of small autotransplants for the treatment of patients with limited vitiligo. The latest application of this technique is reported in this issue of the Archives.11 Falabella, and also Klaus and colleagues,10 exercised sound judgment in using patients with segmental or focal vitiligo in their efforts to repigment skin, because no additional therapy was required to treat the basic defect that had caused the destruction of pigment cells in the first place. The importance of an informed choice of sites for repigmentation is emphasized also by Koga,12 whose findings

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