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January 1989

Vesicular Jarisch-Herxheimer Reaction

Author Affiliations

From the Department of Dermatology, Baylor College of Medicine, Houston. Dr Cochran is in private practice in Bay City, Tex.

Arch Dermatol. 1989;125(1):77-81. doi:10.1001/archderm.1989.01670130079010

• The Jarisch-Herxheimer reaction is a self-limited, febrile episode that may occur following antibiotic therapy for syphilis. We report four cases of a heretofore unrecognized vesicular variant of the Jarisch-Herxheimer reaction. It is important to distinguish this phenomenon from an allergic drug eruption.

(Arch Dermatol 1989;125:77-81)