[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.167.142.229. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
March 1989

Clinics in Dermatology: Pseudoxanthoma Elasticum

Author Affiliations

Philadelphia

 

by Kenneth H. Neldner, 159 pp, with color and black-and-white illustrations, $30, Philadelphia, JB Lippincott, 1988.

Arch Dermatol. 1989;125(3):446. doi:10.1001/archderm.1989.01670150136028

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.

Abstract

Pseudoxanthoma elasticum (PXE) is a puzzling heritable disorder of elastic fibers. Even though the disease has been recognized for more than a hundred years, little is known of its natural history, and essentially no treatment is available. Moreover, this is a disorder that often goes undiagnosed for needlessly long periods, and, when diagnosed, either false or misleading information is often given to the patient, causing unwarranted anxiety. This sharply focused textbook addresses primarily the clinical facets of PXE. Specifically, the author, Dr Neldner, shares the wealth of his clinical expertise on this disease by summarizing data on 100 patientswith PXE who were followed up over the ten-year period from 1973 to 1983. The observations dispel many myths concerning PXE and clarify a variety of prognostic features, among which are the following: the overall survivorship is probably better than has been previously suggested; in most cases, PXE is inherited as an

First Page Preview View Large
First page PDF preview
First page PDF preview
×