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October 1989

Cutaneous Bipolaris spicifera Infection

Author Affiliations

From the Departments of Dermatology (Drs Straka and Cooper) and Pathology (Drs Cooper and Body), University of Virginia Health Sciences Center, Charlottesville.

Arch Dermatol. 1989;125(10):1383-1386. doi:10.1001/archderm.1989.01670220079013

Bipolaris spicifera is a dematiaceous fungus that has rarely been reported to cause cutaneous infection in humans. A patient with leukemia was examined for a nonhealing ulcer on her leg that developed following minor trauma. Histopathologic study revealed groups of nonpigmented, septate fungal hyphae located predominantly in the necrotic ulcer base. Cultures of a biopsy specimen yielded colonies that were gray to black with a black reverse. Microscopic examination revealed dematiaceous, straight, oblong conidia consistent with B spicifera. The ulcer was successfully treated with surgical excision, skin graft, and amphotericin B.

(Arch Dermatol. 1989;125:1383-1386)