REPORT OF A CASE
A 39-year-old man presented with a 1-month history of pain in a large plaque located over the right foot. Results of a physical examination revealed an otherwise apparently normal, healthy man with a large, red-violaceous plaque over almost the entire right sole, and extending over the lateral side of the foot (Fig 1). The plaque was extremely painful to palpation.Microscopic examination revealed many islands of eccrine glands located in the deep dermis. The numerous eccrine structures were surrounded by mature collagenous tissue. Also, numerous capillary angiomatous channels surrounded and were intermingled with these eccrine structures (Fig 2). Electron microscopic examination revealed an increase in number and size of the eccrine glands, which were otherwise normal appearing. Staining for S100 protein showed small nerves present among the eccrine glands.
Eccrine angiomatous hamartoma.
Although benign, there was extreme pain associated with the lesion. The involvement of almost the entire right sole made surgical intervention a diffic
Wolf R, Krakowski A, Dorfman B, Baratz M. Eccrine Angiomatous HamartomaA Painful Step. Arch Dermatol. 1989;125(11):1489-1490. doi:10.1001/archderm.1989.01670230031005