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Article
November 1989

Jessner's Lymphocytic Infiltration of the SkinA Clinical Study of 100 Patients

Author Affiliations

From the Departments of Dermatology, University Hospital, Utrecht (Drs Toonstra, Wildschut, and van Vloten), Deventer Hospitals, Deventer (Drs Boer, Smeenk, and Boonstra), and Free University Hospital, Amsterdam (Dr Willemze); and the Institute of Pathology, University Hospital, Utrecht (Dr van der Putte), the Netherlands.

Arch Dermatol. 1989;125(11):1525-1530. doi:10.1001/archderm.1989.01670230067010
Abstract

• Jessner's lymphocytic infiltration of the skin is a well-known but poorly understood disorder. Some doubt still exists about whether it is a single entity or a heterogeneous group that can pass into polymorphous light eruption, discoid lupus erythematosus, or even malignant lymphoma. Therefore, a large number of patients with lymphocytic infiltration of the skin (N = 100; 46 male, 54 female) were examined to elucidate these questions. We conclude that lymphocytic infiltration of the skin is a single entity. Progression into polymorphous light eruption, discoid lupus erythematosus, or lymphoma was not observed. However, this study shows that lymphocytic infiltration of the skin and polymorphous light eruption can occur simultaneously in 1 patient. In this study the cases of 10 patients with this combination are reported. An effective but harmless therapy is yet unknown. Intermittent use of topical steroids can be useful but is not effective in many patients.

(Arch Dermatol. 1989;125:1525-1530)

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