This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.
Adverse Reactions to Drug Formulation Agents: A Handbook of Excipients is volume 14 of the Marcel Dekker series in clinical pharmacology. Dr Murray Weiner is acting director of the Division of Clinical Pharmacology and Toxicology and clinical professor of medicine, University of Cincinnati (Ohio). Dr I. Leonard Bernstein is clinical professor of medicine and environmental health sciences and codirector of the Allergy Research Laboratory and the Allergy Training Program, University of Cincinnati Medical School.
In this volume, the term excipient is broadly applied to include all agents in a medicinal preparation regardless of their nature, purpose, or quantities employed, other than the components intended as the "active" ingredients. Until recently, very little attention has been paid to these presumably inactive excipients. Now, however, we have become aware that these inactive ingredients may indeed be very active and capable of producing serious side effects of importance to all physicians, particularly the
Fisher A. Adverse Reactions to Drug Formulation Agents. Arch Dermatol. 1990;126(3):408. doi:10.1001/archderm.1990.01670270140032