• A 63-year-old woman with fibrous histiocytomas showed cholesterol deposition in the setting of type IIB hyperlipidemia. The two lesions involved the left leg and right thigh. One had typical features of a fibrous histiocytoma including changes of the overlying epidermis. The other was essentially replaced by cholesterol deposits and could not be differentiated from a tuberous xanthoma. This case illustrates the histiocytic response of fibrous histiocytomas to a hyperlipoproteinemic microenvironment.
(Arch Dermatol. 1990;126:506-508)
Hunt SJ, Cruz DJS, Miller CW. Cholesterotic Fibrous HistiocytomaIts Association With Hyperlipoproteinemia. Arch Dermatol. 1990;126(4):506-508. doi:10.1001/archderm.1990.01670280090016