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April 1990

Cholesterotic Fibrous HistiocytomaIts Association With Hyperlipoproteinemia

Author Affiliations

From Cutaneous Pathology, St John's Mercy Medical Center (Drs Hunt and Santa Cruz), and the Division of Dermatology, Department of Medicine, Washington University School of Medicine (Dr Miller), St Louis, Mo.

Arch Dermatol. 1990;126(4):506-508. doi:10.1001/archderm.1990.01670280090016

• A 63-year-old woman with fibrous histiocytomas showed cholesterol deposition in the setting of type IIB hyperlipidemia. The two lesions involved the left leg and right thigh. One had typical features of a fibrous histiocytoma including changes of the overlying epidermis. The other was essentially replaced by cholesterol deposits and could not be differentiated from a tuberous xanthoma. This case illustrates the histiocytic response of fibrous histiocytomas to a hyperlipoproteinemic microenvironment.

(Arch Dermatol. 1990;126:506-508)