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We appreciate your thoughtful and well-considered comments regarding our article. None of the patients described in our study were receiving zidovudine. We have not excluded the possibility of insects being causative for the lesion we have described, and share your view that they may represent an atypical reaction or "amnestic" response to a prior insect bite. Unfortunately, we do not have data to support or refute this hypothesis.
Johnson WD. Pruritic Skin Eruption in the Acquired Immunodeficiency Syndrome: Arthropod Bites?-Reply. Arch Dermatol. 1990;126(4):539. doi:10.1001/archderm.1990.01670280125029