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June 1990

Cutaneous Manifestations of Pseudomonas Infection in the Acquired Immunodeficiency Syndrome

Author Affiliations

Division of Infectious Diseases Department of Internal Medicine Veterans Administration Medical Center University of Michigan Medical School 2215 Fuller Rd Ann Arbor, MI 48105

Arch Dermatol. 1990;126(6):832-833. doi:10.1001/archderm.1990.01670300132031

To the Editor.—  Infection with Pseudomonas aeruginosa has been associated with several dermatologic manifestations, including cellulitis, folliculitis, pustules, small papules and plaques, ecthyma gangrenosum, and subcutaneous nodules.1-3 Except for healthy individuals with apocrine folliculitis, patients with these skin manifestations are most often immunocompromised and frequently neutropenic.1,2,4Bacterial skin infections in patients with the acquired immunodeficiency syndrome (AIDS) are uncommon. Acne, folliculitis, and staphylococcal furuncles have been noted in less than 5% of AIDS patients.5 We describe two AIDS patients who were not neutropenic and who presented with nodular skin lesions and systemic manifestations of infection due to P aeruginosa.

Report of Cases.—Case 1.—  A 37-year-old man with AIDS manifested by Kaposi's sarcoma and Pneumocystis carinii pneumonia developed fevers to 40°C, meningeal signs, and three tender, erythematous, firm, nonfluctuant, red nodules ranging from 5 to 20 mm in diameter on his foot and lower back

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