REPORT OF A CASE
A 60-year-old man presented for evaluation of a skin lesion on his chest. The lesion was asymptomatic and was of unknown duration.Physical examination revealed a single, nontender, flesh-colored nodule above the right nipple (Fig 1).A shave biopsy was performed and a representative section is shown in Fig 2.
The biopsy specimen contained long, thin, branching, anastomosing, epithelial strands embedded in a fibrous stroma. Small buds were seen projecting from the epithelial strands, with many of the strands showing connections to the surface epidermis.What is your diagnosis?
Fibroepithelioma of Pinkus.
Fibroepithelioma of Pinkus is thought to be a variant of basal cell carcinoma. Pinkus1 identified this entity in 1953 when he described a "peculiar fibroepithelial tumor" occurring in 4 of 900 cases of basal cell carcinoma. He stressed that these tumors did "not constitute a new entity," but rather "an unusual variety of
Scherbenske JM, Kopeloff IH, Turiansky G, Sau P. A Solitary Nodule on the Chest. Arch Dermatol. 1990;126(7):958a-958b. doi:10.1001/archderm.1990.01670310121022