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August 1990

Disseminated Mycobacterium chelonae subspecies chelonae Infection With Cutaneous and Osseous Manifestations

Author Affiliations


From the Infectious Disease (Dr Drabick) and Medicine (Dr Duffy) Services and the Department of Dermatology (Drs Samlaska and Scherbenske), Walter Reed Army Medical Center, Washington, DC.

Arch Dermatol. 1990;126(8):1064-1067. doi:10.1001/archderm.1990.01670320088016

† A 75-year-old man who had been receiving corticosteroids for treatment of chronic obstructive pulmonary disease presented with nodulopustular skin lesions, bone pain, and constitutional symptoms. Evaluation revealed a disseminated infection with Mycobacterium chelonae subspecies chelonae, with cutaneous and osseous involvement documented by histopathologic studies and cultures. The bone involvement is a novel observation for this subspecies. The patient was successfully treated with a three-drug regimen of tobramycin sulfate, erythromycin stearate, and ciprofloxacin hydrochloride. We present a discussion of the case in the context of the literature.

(Arch Dermatol. 1990;126:1064-1067)