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Article
November 1990

Thrombocytopenia-Absent Radii Syndrome and Lack of Response to the Pulsed Dye Laser

Author Affiliations

Department of Dermatology New York University Medical Center 530 First Ave New York, NY 10016

Arch Dermatol. 1990;126(11):1520-1521. doi:10.1001/archderm.1990.01670350136030
Abstract

To the Editor.—  The Thrombocytopenia-Absent Radii (TAR) syndrome is a congenital syndrome encompassing several maladies. Foreshortening of the forearms and radially deviated hands are noted in all cases. In addition, patients always have thrombocytopenia with abnormal megakaryocytes in the bone marrow.1-4 The thrombocytopenia usually presents at birth or during the neonatal period, can be very severe with significant morbidity, but usually resolves after the first year of life.The TAR syndrome may be inherited in an autosomal recessive pattern, although alternate modes of transmission have also been proposed.1-4 Several patients have also had port-wine stains of the head and neck region.2-4The patient with TAR syndrome who is presented here also has an extensive port-wine stain. The flashlamp-pumped pulsed dye laser (PDL) had no effect on his port-wine stain with no lightening seen after three test treatments. We postulate that his severe thrombocytopenia prevented the formation of

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