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December 1990

Spindle and Epithelioid Cell Nevus (Spitz Nevus)Natural History Following Biopsy

Author Affiliations

From the Department of Dermatology, Division of Dermatopathology, University of Minnesota Hospital and Clinic, Minneapolis (Dr Kaye), and the Department of Pathology, The Lauren V. Ackerman Laboratory of Surgical Pathology, Division of Anatomic Pathology, Washington University Medical Center and Barnes Hospital, St Louis, Mo (Dr Dehner).

Arch Dermatol. 1990;126(12):1581-1583. doi:10.1001/archderm.1990.01670360045005

• A clinical follow-up study of 49 cases of spindle and epithelioid cell nevus is presented to address the question about the potential for local recurrence. Only 19 (39%) of the 49 lesions were initially excised en toto, and the remainder (30 cases) had positive margins; six of the latter spindle and epithelioid cell nevi were reexcised, and no evidence of a residual nevus was found in five of the six cases. There were no recurrences in the 49 patients during an average follow-up period of 5.0 years (range, 1 to 10 years). The rarity of recurrent spindle and epithelioid cell nevus would justify a conservative approach to management, with clinical follow-up alone recommended after a subtotal excision, when the pathologic diagnosis is unequivocal.

(Arch Dermatol. 1990;126:1581-1583)