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December 1990

Unusual Skin Tumors in Langerhans' Cell Histiocytosis

Author Affiliations

From the Departments of Medicine (Drs Santhosh-Kumar, Al Momen, and Arajim), Pathology (Dr Shipkey), and Electron Microscopy (Dr Kyriacou), King Khalid University, Riyadh, Saudi Arabia. Dr Santhosh-Kumar is now with the University of Colorado Health Sciences Center, Denver, and Dr Shipkey is presently with the University of Mississippi Medical Center, Jackson.

Arch Dermatol. 1990;126(12):1617-1620. doi:10.1001/archderm.1990.01670360081014

• A case of Langerhans' cell histiocytosis with unusual skin manifestations in the form of multiple large skin tumors is described. The skin lesions responded partially to chemotherapy with etoposide and prednisone, and residual lesions were excised surgically. The patient developed central diabetes insipidus during treatment.

(Arch Dermatol. 1990;126:1617-1620)