• A multiple puncture technique using a bifurcated vaccination needle to introduce bleomycin sulfate (1 U/mL sterile saline solution) into warts resulted in elimination of 92% of a random series of 258 warts after a single treatment. Recurrence was not observed during a 6-month follow-up period. Six of the 66 patients required two to seven treatments for wart eradication, and four patients requested alternative therapy after initial failure with a single bleomycin treatment.
(Arch Dermatol. 1991;127:234-236)
Shelley WB, Shelley ED. Intralesional Bleomycin Sulfate Therapy for WartsA Novel Bifurcated Needle Puncture Technique. Arch Dermatol. 1991;127(2):234-236. doi:10.1001/archderm.1991.01680020102014