[Skip to Content]
[Skip to Content Landing]
February 1991

Intralesional Bleomycin Sulfate Therapy for WartsA Novel Bifurcated Needle Puncture Technique

Author Affiliations

From the Division of Dermatology, Department of Medicine, Medical College of Ohio, Toledo.

Arch Dermatol. 1991;127(2):234-236. doi:10.1001/archderm.1991.01680020102014

• A multiple puncture technique using a bifurcated vaccination needle to introduce bleomycin sulfate (1 U/mL sterile saline solution) into warts resulted in elimination of 92% of a random series of 258 warts after a single treatment. Recurrence was not observed during a 6-month follow-up period. Six of the 66 patients required two to seven treatments for wart eradication, and four patients requested alternative therapy after initial failure with a single bleomycin treatment.

(Arch Dermatol. 1991;127:234-236)