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Article
March 1991

Therapy of Advanced Melanoma: Pigment Cell

Author Affiliations

Boston, Mass

 

vol 10, edited by Philip Rumke, 230 pp, with illus, $132, New York, NY, S Karger AG, 1990.

Arch Dermatol. 1991;127(3):433. doi:10.1001/archderm.1991.01680030159031

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Abstract

The rising mortality rates for melanoma have stimulated many approaches in research in the attempt to treat this tumor. This monograph presents an up-to-date summary of recent therapeutic considerations in advanced and metastatic melanoma.

Those approaches include surgery, radiotherapy, chemotherapy, immunotherapy, limb perfusion, monoclonal antibody therapy, and metabolic-based treatment. Of the 13 chapters in this monograph, four are devoted to immunotherapy, reflecting the rapid advances that have emerged in this area over the last 5 years. While there is some overlap in these four chapters, they summarize the inherent excitement in this new approach to metastatic melanoma. The chapter by Kirkwood and colleagues on biological-response modifiers is particularly well done.

Of the remaining chapters, the chapter by Kleeberg and colleagues on chemotherapy has a very thoughtful introduction and is one of the best in this monograph. The excellent chapter by Allan and Cornbleet offers many informative tables and a succinct

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