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Article
April 1991

Sclerosing PanniculitisA Clinicopathologic Assessment

Author Affiliations

From the Departments of Dermatology (Drs Jorizzo, White, and Zanolli) and Pathology (Dr White), Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, NC; Department of Dermatology, University of Virginia, Charlottesville (Dr Greer); Departments of Dermatology and Pathology, Emory University Medical Center, Atlanta, Ga (Dr Solomon). DrJetton is in private practice in Greenville, SC.

Arch Dermatol. 1991;127(4):554-558. doi:10.1001/archderm.1991.04510010122016
Abstract

† Six patients with well-circumscribed, indurated, inflammatory plaques of the lower extremity are described. Incisional biopsy specimens in each patient revealed fat necrosis, sclerosis, and a lobular panniculitis. These patients are similar to those described under the designations hypodermitis sclerodermaformis or lipodermatosclerosis. The name sclerosing panniculitis is proposed to unify these conditions. The pathogenesis is unknown, although a role for venous stasis or previous thrombophlebitis has been proposed. Systemic or local anti-inflammatory therapies have not been clinically effective.

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