• Systemic corticosteroids may be either contraindicated or not efficacious in treating the cutaneous manifestations occurring in 20% to 35% of patients with systemic sarcoidosis. Chloroquine phosphate has been reported to be a valuable alternative therapy for cutaneous lesions of sarcoidosis. With a judiciously determined daily dosage and regular 6-month ophthalmologic follow-up examinations, the risk of developing retinopathy can be avoided, because the daily dosage rate rather than total dose accumulation determines the development of chloroquine-induced retinopathy. We reviewed the efficacy and safety of chloroquine and its role in the treatment of cutaneous sarcoidosis.
(Arch Dermatol. 1991;127:1034-1040)
Zic JA, Horowitz DH, Arzubiaga C, King LE. Treatment of Cutaneous Sarcoidosis With ChloroquineReview of the Literature. Arch Dermatol. 1991;127(7):1034-1040. doi:10.1001/archderm.1991.01680060108015