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Article
July 1991

Basic Life Sciences, vol 53, DNA Damage and Repair in Human Tissues

Author Affiliations

Boston, Mass

 

edited by Betsy M. Sutherland and Avril D. Woodhead, 464 pp, $95, New York, NY, Plenum Press, 1990.

Arch Dermatol. 1991;127(7):1089-1090. doi:10.1001/archderm.1991.01680060165039

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Abstract

This book is a collection of 33 articles, representing the proceedings of a symposium on DNA damage and repair held at Brookhaven National Laboratory, Upton, NY, in October 1989. The articles encompass a broad area, covering a number of aspects of DNA damage and repair both in vitro and in vivo. The symposium organizers have grouped the articles into seven major categories, including methodology for measurement of DNA lesions, aspects of DNA damage and repair in human skin, biochemical and molecular mechanisms, model systems for human skin, DNA damage and repair in blood cells, DNA damage and repair in internal organs, and detection of DNA damage at the level of the whole organism. Dermatologists will probably find the first half of the book of particular interest, since it is devoted primarily to human skin. The first few articles in the book describe current methods for analyzing adducts in DNA by

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