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September 1991

Generalized Pustular Psoriasis and Idiopathic Hypoparathyroidism

Author Affiliations

Department of Dermatology; Department of Endocrinology; Department of Dermatology University of Granada Hospital E-18012 Granada, Spain

Arch Dermatol. 1991;127(9):1418-1419. doi:10.1001/archderm.1991.01680080158027

To the Editor.—  Although the cause of psoriasis remains obscure, some factors are known to be able to trigger or aggravate the disease. Agents that can induce a generalized form of psoriasis include drugs, sunlight, and more rarely metabolic disorders such as hypocalcemia.1Adult-onset idiopathic hypoparathyroidism is an uncommon disease that appears with hypocalcemia,2 and whose association with the development of a generalized form of psoriasis has been only rarely reported.1 We present a patient who developed a generalized pustular psoriasis associated with severe hypocalcemia secondary to idiopathic hypoparathyroidism.

Report of a Case.—  71-year-old man was admitted to the Department of Dermatology in July 1989 with a 15-day history of generalized cutaneous eruption, elevated temperature (39°C), and general malaise. His antecedents included vulgaris psoriasis on the elbows and the lumbar region, which had been left untreated for the last 25 years, bilateral fachectomy (extirpation of crystalline lens

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